Egfr-IN-7(TQB3804 )

Names

[ Name ]:
Egfr-IN-7(TQB3804 )

Biological Activity

[Description]:

EGFR-IN-7 (compound 34) is a selective and potent EGFR kinase inhibitor extracted from patent WO2019015655A1, has IC50s of 7.92 nM and 0.218 nM for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) respectively, and shows anti-tumor activity[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> JAK/STAT Signaling >> EGFR

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR

[Target]

EGFR (WT):7.92 nM (IC50)

EGFR (C797S/T790M/L858R):0.218 nM (IC50)

[References]

[1]. Aryl-phosphorus-oxygen compound as egfr kinase inhibitor.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₂H₄₁BrN₉O₂P

[ Molecular Weight ]:
694.60

Egfr-IN-7(TQB3804 )

Names

Biological Activity

Chemical & Physical Properties

Related Compounds