Ethylene diacrylate

Names

[ Name ]:
Ethylene diacrylate

[Synonym ]:
ethyleneglycol diacrylate
1,2-dimethacryloyloxyethane
Ethylene diacrylate
Ethylene diacrylate,stabilized
1,2-ethanediyl diacrylate
ethane-1,2-diyl bis(2-methylpropanoate)
ethylene glycol diisobutyrate
ehylene glycol dimethyl acrylate
ethane-1,2-diyl diacrylate
1,2-bis(2-methyl-propanoyloxy)-ethane
ethylene glycol di(2-methylpropanoate)
ethylene glycol dimethacrylate
1,2-Ethanediyl bisacrylate
ethane-1,2-diyl bisprop-2-enoate
EINECS 218-886-4
ethylene glycol diacrylate
Aethylengylkol-diisobutyrat
MFCD00008629
ETHYLENE GLYCOL DIPROPENOATE
2-Propenoic acid, 1,2-ethanediyl ester
Ethane-1,2-diyl bisacrylate

Biological Activity

[Description]:

Ethylene glycol diacrylate (Ethylene diacrylate) is a cross-linking homobifunctional reagent. Ethylene glycol diacrylate can be polymerized to form poly(ethylene glycol) diacrylate for drug delivery[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Ke Luo, et al. On shockwave propagation and attenuation in poly(ethylene glycol) diacrylate hydrogels. J Mech Behav Biomed Mater. 2021 Jun;118:104423.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
223.9±13.0 °C at 760 mmHg

[ Melting Point ]:
184-193℃

[ Molecular Formula ]:
C₈H₁₀O₄

[ Molecular Weight ]:
170.163

[ Flash Point ]:
104.9±18.2 °C

[ Exact Mass ]:
170.057907

[ PSA ]:
52.60000

[ LogP ]:
1.68

[ Appearance of Characters ]:
Liquid | Clear colorless to light yellow

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.447

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AT0350000

CHEMICAL NAME :: Acrylic acid, ethylene ester

CAS REGISTRY NUMBER :: 2274-11-5

BEILSTEIN REFERENCE NO. :: 1771527

LAST UPDATED :: 199710

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C8-H10-O4

MOLECULAR WEIGHT :: 170.18

WISWESSER LINE NOTATION :: 1U1VO2OV1U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - excitement Behavioral - muscle contraction or spasticity

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 350 mg/m3

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - excitement Behavioral - muscle contraction or spasticity

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 570 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 16500 nmol/L

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 17,264,1991

Safety Information

[ Symbol ]:

GHS06, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H312 + H332-H315-H319-H335-H411

[ Precautionary Statements ]:
P261-P273-P280-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S26;S36/S37/S39

[ RIDADR ]:
UN 2810 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
AT0350000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2916190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2916190090

[ Summary ]:
2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%