Enfenamic acid

Names

[ CAS No. ]:
23049-93-6

[ Name ]:
Enfenamic acid

[Synonym ]:
Enfenamic acid
N-phenylethylanthranilic acid
N-Phenethylanthranilic acid
RH-8
Tromaril

Biological Activity

[Description]:

Enfenamic acid is a nonsteroidal anti-inflammatory agent. Enfenamic acid suppresses wound healing[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Rao CM, et al. Effects of enfenamic acid and its zinc salt on wound-healing. Indian J Physiol Pharmacol. 1988;32(1):61-66.

[2]. Diwan PV, et al. Effects of nonsteroidal antiinflammatory agents (NSAIAs) on wound healing. Indian J Exp Biol. 1986;24(10):640-643.

Chemical & Physical Properties

[ Density]:
1.214g/cm3

[ Boiling Point ]:
452.3ºC at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₅NO₂

[ Molecular Weight ]:
241.28500

[ Flash Point ]:
227.4ºC

[ Exact Mass ]:
241.11000

[ PSA ]:
49.33000

[ LogP ]:
3.11240

[ Vapour Pressure ]:
5.7E-09mmHg at 25°C

[ Index of Refraction ]:
1.643

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DH6286100

CHEMICAL NAME :: Benzoic acid, 2-(phenethylamino)-

CAS REGISTRY NUMBER :: 23049-93-6

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C15-H15-N-O2

MOLECULAR WEIGHT :: 241.31

WISWESSER LINE NOTATION :: QVR BM2R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 575 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: Cytogenetic analysis

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 3 gm/kg/5D (Continuous)

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 170,41,1986

Safety Information

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%