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Heveaflavone

Names

[ CAS No. ]:
23132-13-0

[ Name ]:
Heveaflavone

[Synonym ]:
2-oxo-7-methylhypoxanthine
Heveaflavone
5-Hydroxy-8-[2-hydroxy-5-(5-hydroxy-7-methoxy-4-oxo-4H-chromen-2-yl)phenyl]-7-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one
I-7-,II-7-,II-4'-tri-O-methylamentoflavone
Heteroxanthine
7-Methylxanthin
1-methylxanthine
Heteroxanthin
4H-1-Benzopyran-4-one, 5-hydroxy-8-[2-hydroxy-5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)phenyl]-7-methoxy-2-(4-methoxyphenyl)-
Xanthine,7-methyl
2,6-Dihydroxy-7-methylpurine
7-methyl-3,7-dihydro-1H-purine-2,6-dione
Heveaflavon
7-methyl-xanthine
7-methylxantine
3,7-Dihydro-7-methyl-1H-purine-2,6-dione

Biological Activity

[Description]:

Heveaflavone is an anticancer and antioxidant agent[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[In Vitro]

Heveaflavone 具有抗增殖效果，对 PC-9、CNE2、HL60、A549 和 K562 细胞的 IC50 分别为 6.74±2.1、15.8±2.9、46.0±4.6、>50 和 >50 μg/mL[1]。

[References]

[1]. Li S, et al. Preparative isolation of six anti-tumour biflavonoids from Selaginella doederleinii Hieron by high-speed counter-current chromatography. Phytochem Anal. 2014 Mar-Apr;25(2):127-33.  

[2]. Wang G, et al. Rapid Screening and Structural Characterization of Antioxidants from the Extract of Selaginella doederleinii Hieron with DPPH-UPLC-Q-TOF/MS Method. Int J Anal Chem. 2015;2015:849769.  

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
842.5±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C33H24O10

[ Molecular Weight ]:
580.54

[ Flash Point ]:
277.2±27.8 °C

[ Exact Mass ]:
580.136963

[ PSA ]:
148.80000

[ LogP ]:
4.71

[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C

[ Index of Refraction ]:
1.684

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds