Glycoborinine

Names

[ Name ]:
Glycoborinine

[Synonym ]:
Pyrano[2,3-c]carbazol-9-ol, 3,7-dihydro-3,3,10-trimethyl-
3,3,10-Trimethyl-3,7-dihydropyrano[2,3-c]carbazol-9-ol

Biological Activity

[Description]:

Glycoborinine, a natural carbazole alkaloid, can be isolated from Glycosmis pentaphylla. Glycoborinine induces HepG2 cell apoptosis through mitochondrial pathway. Glycoborinine also inhibits HIV replication in cells[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

Signaling Pathways >> Anti-infection >> HIV

Research Areas >> Infection

[References]

[1]. Yang H, et al. Glycoborinine induces apoptosis through mitochondrial pathway in HepG2 cells. J Asian Nat Prod Res. 2014 Oct;16(10):991-9.

[2]. Yang JH, et al. Carbazole Alkaloids from Clausena anisum-olens: Isolation, Characterization, and Anti-HIV Evaluation. Molecules. 2019 Dec 26;25(1):99.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
508.6±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₈H₁₇NO₂

[ Molecular Weight ]:
279.33

[ Flash Point ]:
261.4±30.1 °C

[ Exact Mass ]:
279.125916

[ LogP ]:
4.85

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.707

[ Storage condition ]:
2-8℃