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TP-16

Names

[ CAS No. ]:
2332972-26-4

[ Name ]:
TP-16

Biological Activity

[Description]:

TP-16 is a novel and selective EP4 antagonist with an IC50 of 2.1 nM.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor

[Target]

Prostaglandin Receptor:2.1 nM (IC50)

[References]

[1]. Lu W, et al. Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer. EMBO Mol Med. 2021 Jan 11;13(1):e12798.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₂FNO₄S

[ Molecular Weight ]:
439.50

Related Compounds