5-Fluorocytidine

Names

[ Name ]:
5-Fluorocytidine

[Synonym ]:
4-Amino-5-fluor-1-(β-D-ribofuranosyl)pyrimidin-2(1H)-on
5-fluoro-cytidine
5-Fluorocytidine
fluorocytidine
4-Amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-fluoro-2(1H)-pyrimidinone
Cytidine, 5-fluoro-
5-Fluoro-D-cytidine
EINECS 234-122-2
5-fluoro-cytidin
L-5-Fluorocytidine
5-fluoro-2'-deoxycytidine
MFCD00210953
L-β-Ribofuranosyl-5-fluoro-cytosine
5-Fluorcytidin

Biological Activity

[Description]:

5-Fluorocytidine is a member of cytidines, inhibits maturation of the 45S ribosomal RNA precursor[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Density]:
2.0±0.1 g/cm3

[ Boiling Point ]:
511.4±60.0 °C at 760 mmHg

[ Melting Point ]:
196-200 °C(lit.)

[ Molecular Formula ]:
C₉H₁₂FN₃O₅

[ Molecular Weight ]:
261.207

[ Flash Point ]:
263.1±32.9 °C

[ Exact Mass ]:
261.076111

[ PSA ]:
130.83000

[ LogP ]:
-1.67

[ Vapour Pressure ]:
0.0±3.0 mmHg at 25°C

[ Index of Refraction ]:
1.732

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HA3890000

CHEMICAL NAME :: Cytidine, 5-fluoro-

CAS REGISTRY NUMBER :: 2341-22-2

LAST UPDATED :: 198508

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C9-H12-F-N3-O5

MOLECULAR WEIGHT :: 261.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Rodent - mouse Leukocyte

DOSE/DURATION :: 100 ug/L

REFERENCE :: CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 30,1018,1982

Safety Information

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ WGK Germany ]:
3

[ RTECS ]:
HA3890000

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%