Hoechst 33258
Names
[ CAS No. ]:
23491-44-3
[ Name ]:
Hoechst 33258
[Synonym ]:
4-[5-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1,3-dihydrobenzimidazol-2-ylidene]cyclohexa-2,5-dien-1-one
Pibenzimol HCl
Pibenzimol
Bisbenzimidazole
EINECS 245-689-0
Hoechst 33258
Biological Activity
[Description]:
[Related Catalog]:
[Target]
IC50: 51.31±4.56 μM (HeLa cell), 32.43±3.27 μM (HL60 cell), 15.42 ± 2.16 μM (U937 cell)[1]
[In Vitro]
[Cell Assay]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.337 g/cm3
[ Boiling Point ]:
643.1ºC at 760 mmHg
[ Melting Point ]:
314ºC
[ Molecular Formula ]:
C25H24N6O
[ Molecular Weight ]:
424.49800
[ Flash Point ]:
342.7ºC
[ Exact Mass ]:
424.20100
[ PSA ]:
84.07000
[ LogP ]:
4.23350
[ Vapour Pressure ]:
0mmHg at 25°C
[ Index of Refraction ]:
1.742
[ Storage condition ]:
-20℃
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SM1140475
- CHEMICAL NAME :
- Phenol, p-(5-(5-(4-methyl-1-piperazinyl)-2-benzimidazolyl)-2- benzimidazolyl)-
- CAS REGISTRY NUMBER :
- 23491-44-3
- LAST UPDATED :
- 199703
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C25-H24-N6-O
- MOLECULAR WEIGHT :
- 424.55
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 80 ug/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 329,19,1995
Safety Information
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
26-36