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E3 ligase Ligand-Linker Conjugates 41

Names

[ CAS No. ]:
2357114-75-9

[ Name ]:
E3 ligase Ligand-Linker Conjugates 41

Biological Activity

[Description]:

E3 ligase Ligand-Linker Conjugates 41 incorporates a cIAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 41 can be used to design PROTAC degrader[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[Target]

cIAP1


[References]

[1]. Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78.

Chemical & Physical Properties

[ Molecular Formula ]:
C41H59N5O9S

[ Molecular Weight ]:
798.00

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds