H-Phe-Gly-Gly-OH

Names

[ Name ]:
H-Phe-Gly-Gly-OH

[Synonym ]:
phe-gly-gly
Phe-Gly-Gly-OH
L-phenylalanyl=>glycyl=>glycine
2-[[2-[[(2S)-2-amino-3-phenylpropanoyl]amino]acetyl]amino]acetic acid
Phenylalanyl-glycyl-glycine
H-Phe-Gly-Gly-OH

Biological Activity

[Description]:

L-Phenylalanylglycylglycine is a Glycine (HY-Y0966) derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.296 g/cm3

[ Boiling Point ]:
667.3ºC at 760 mmHg

[ Molecular Formula ]:
C₁₃H₁₇N₃O₄

[ Molecular Weight ]:
279.29200

[ Flash Point ]:
357.4ºC

[ Exact Mass ]:
279.12200

[ PSA ]:
121.52000

[ LogP ]:
0.35550

[ Vapour Pressure ]:
1.02E-18mmHg at 25°C

[ Index of Refraction ]:
1.576

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Tissue alkaline phosphatase is involved in lipid metabolism and gene expression and secretion of adipokines in adipocytes.

Biochim. Biophys. Acta 1850 , 2485-96, (2015)

Alkaline phosphatases are dimeric hydrolytic enzymes that dephosphorylate nucleotides and proteins. AP-TNAP is found primarily in skeletal tissues were it plays a major role in the mineralization of t...

Structure of isolated tryptophyl-glycine dipeptide and tryptophyl-glycyl-glycine tripeptide: ab initio SCC-DFTB-D molecular dynamics simulations and high-level correlated ab initio quantum chemical calculations.

J. Phys. Chem. B 110 , 6385-6396, (2006)

The tryptophyl-glycine (Trp-Gly) and tryptophyl-glycyl-glycine (Trp-Gly-Gly) peptides have been studied by means of molecular dynamic simulations combined with high-level correlated ab initio quantum ...

Limitations of electrospray ionization in the analysis of a heterogeneous mixture of naturally occurring hydrophilic and hydrophobic compounds.

Rapid Commun. Mass Spectrom. 24 , 3163-3170, (2010)

A model heterogeneous mixture of a hydrophilic tripeptide (phenylalanine-glycine-glycine, PGG) and hydrophobic organic acids ((12)C- and (13)C-octanoic acid and pentadecanoic acid) was subjected to el...