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PROTAC CRBN Degrader-1

Names

[ CAS No. ]:
2358775-70-7

[ Name ]:
PROTAC CRBN Degrader-1

Biological Activity

[Description]:

PROTAC CRBN Degrader-1 comprises a cereblon (CRBN) ligand binding group, a linker and an von Hippel-Landau (VHL) binding group. PROTAC CRBN Degrader-1 is an cereblon (CRBN) degrader[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC
Signaling Pathways >> PROTAC >> Ligand for E3 Ligase

[References]

[1]. Girardini M, et al. Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs. Bioorg Med Chem. 2019 Jun 15;27(12):2466-2479.

Chemical & Physical Properties

[ Molecular Formula ]:
C53H72N8O13S

[ Molecular Weight ]:
1061.25

[ Storage condition ]:
2-8°C

Related Compounds