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ALK-IN-9

Names

[ CAS No. ]:
2359662-39-6

[ Name ]:
ALK-IN-9

Biological Activity

[Description]:

ALK-IN-9 (compound 40) is a potent ALK inhibitor. ALK-IN-9 inhibits cell proliferation with IC50s of <0.2 nM, <0.2 nM, 0.2 nM for Ba/F3-EML4-ALK, KM 12 (TPM3-TRKA), KG-l cell (OP2-FGFR1), respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ALK

[References]

[1]. Evan W. ROGERS, et al. Inhibiteurs macrocycliques de kinase et leur utilisation. US20160159741A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H21FN6O3

[ Molecular Weight ]:
412.42

Related Compounds