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VPC-70619

Names

[ CAS No. ]:
2361742-30-3

[ Name ]:
VPC-70619

Biological Activity

[Description]:

VPC-70619 is a potent, orally active N-Myc inhibitor. VPC-70619 blocks the N-Myc-Max heterocomplex from binding to DNA E-boxes and demonstrated strong inhibition activity against N-Myc-dependent cell lines as well as high bioavailability in both oral and intraperitoneal administration[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Apoptosis >> c-Myc

[References]

[1]. Ton AT, et al. Development of VPC-70619, a Small-Molecule N-Myc Inhibitor as a Potential Therapy for Neuroendocrine Prostate Cancer. Int J Mol Sci. 2022;23(5):2588. Published 2022 Feb 26.

Chemical & Physical Properties

[ Molecular Formula ]:
C16H8ClF3N4O

[ Molecular Weight ]:
364.71

Related Compounds