6-hydroxy-4-methylycoumarin

Names

[ Name ]:
6-hydroxy-4-methylycoumarin

[Synonym ]:
Coumarin,6-hydroxy-4-methyl
6-hydroxy-4-methyl-2H-1-benzopyran-2-one
EINECS 219-146-3
6-Hydroxy-4-methylcoumarin, 6-Hydroxy-4-methyl-2-benzopyrone
MFCD00016967
6-hydroxy-4-methylbenzopyran-2[H]-one
6-hydroxy-4-methylcoumarin
2H-1-Benzopyran-2-one, 6-hydroxy-4-methyl-
6-Hydroxy-4-methyl-2H-chromen-2-one
Coumarin, 6-hydroxy-4-methyl-
6-hydroxy-4-methylycoumarin

Biological Activity

[Description]:

6-Hydroxy-4-methylcoumarin (compound 9) is a coumarins secondary metabolites and has anticancer activity[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Guerrero, T. Global reactivity indexes and nonparametric statistics in the study of the proapoptotic activity of coumarins. International Journal of Quantum Chemistry, , e25902.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
391.4±37.0 °C at 760 mmHg

[ Melting Point ]:
246.5-249.5 °C(lit.)

[ Molecular Formula ]:
C₁₀H₈O₃

[ Molecular Weight ]:
176.169

[ Flash Point ]:
181.8±19.3 °C

[ Exact Mass ]:
176.047348

[ PSA ]:
50.44000

[ LogP ]:
2.00

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.611

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ WGK Germany ]:
3

[ RTECS ]:
GN6999800

[ HS Code ]:
2932209090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%