Boc-C1-PEG3-C4-OH

Names

[ Name ]:
Boc-C1-PEG3-C4-OH

Biological Activity

[Description]:

Boc-C1-PEG3-C4-OH is a PROTAC linker, which refers to the alkyl chain composition. Boc-C1-PEG3-C4-OH can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

Alkyl/ether

[References]

[1]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₃₂O₆

[ Molecular Weight ]:
320.42

Safety Information

[ Hazard Codes ]:
Xi

Boc-C1-PEG3-C4-OH

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Related Compounds