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BTK inhibitor 13

Names

[ CAS No. ]:
2376726-26-8

[ Name ]:
BTK inhibitor 13

Biological Activity

[Description]:

BTK inhibitor 13 (compound 8) is a potent and selective Bruton's tyrosine kinase (BTK) inhibitor with an IC50 of 1.2 nM[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

[Target]

1.2 nM (BTK)[1]


[References]

[1]. Pulz R, et al. Design of Potent and Selective Covalent Inhibitors of Bruton's Tyrosine Kinase Targeting an Inactive Conformation. ACS Med Chem Lett. 2019 Sep 6;10(10):1467-1472.

Chemical & Physical Properties

[ Molecular Formula ]:
C29H26FN5O3

[ Molecular Weight ]:
511.55

Related Compounds