MAT2A-IN-3

MAT2A-IN-3 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally high in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-3 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-3 has the potential for the research of cancer diseases (extracted from patent WO2019191470A1, compound 265)[1].

Research Areas >> Cancer

Signaling Pathways >> GPCR/G Protein >> Somatostatin Receptor

[1]. Zenon D. Konteatis, et al. Heterobicyclic inhibitors of mat2a and methods of use for treating cancer. Patent WO2019191470A1.