2-(6-Methoxynaphthalen-2-yl)propanoic acid

Names

[ Name ]:
2-(6-Methoxynaphthalen-2-yl)propanoic acid

[Synonym ]:
dl-2-(6'-methoxy-2'-naphthyl)-propionic acid
piproxen
2-(6-methoxy-naphthalen-2-yl)-propionic acid
DL-Naproxen
(+)-(S)-Naproxen
(2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid
(2S)-2-(6-Methoxy-2-naphthyl)propanoic acid
2-Naphthaleneacetic acid, 6-methoxy-α-methyl-, (S)-
MFCD00439456
2-naphthaleneacetic acid, 6-methoxy-a-methyl-, (aS)-
Naproxen
EINECS 245-969-2
Apronax
Naxen
(+)-2-(6-Methoxy-2-naphthyl)propionic acid
Naprius
(+/-)-Naproxen
Napren
Propionic acid, 2-(6-methoxy-2-naphthyl)-, (+)-
(+)-NAPROXEN
(S)-(+)-6-methoxy-α-methyl-2-naphthaleneacetic acid
ALEVE
(S)-naproxen
Floginax
Bonyl
2-(6-Methoxy-2-naphthyl)propanoic acid
Naxyn
(+/-)-2-(6-Methoxy-2-naphthyl)propionic Acid
(±)-6-Methoxy-α-methyl-2-naphthaleneacetic Acid
(+)-2-(6-methoxynaphth-2-yl)-propionic acid
Anaprox
2-Naphthaleneacetic acid, 6-methoxy-α-methyl-, (αS)-
2-naphthaleneacetic acid, 6-methoxy-a-methyl-
2-NAPHTHALENEACETIC ACID, 6-METHOXY-α-METHYL-, (+)-
NAPRELAN
2-(6-Methoxy-2-naphthyl)propionic acid
(2S)-2-(6-Methoxynaphth-2-yl)propanoic acid
)-2-(6-Methoxy-2-naphthyl)propionic Acid
(+)-6-Methoxy-α-methyl-2-naphthaleneacetic acid
2-Naphthaleneacetic acid, 6-methoxy-α-methyl-
(S)-(+)-Naproxen
Naprosyn

Biological Activity

[Description]:

(±)-Naproxen ((Rac)-Naproxen) is a racemate of Naproxen (HY-15030). Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively.

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Immunology/Inflammation >> COX

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
403.9±20.0 °C at 760 mmHg

[ Melting Point ]:
157ºC

[ Molecular Formula ]:
C₁₄H₁₄O₃

[ Molecular Weight ]:
230.259

[ Flash Point ]:
154.5±15.3 °C

[ Exact Mass ]:
230.094299

[ PSA ]:
46.53000

[ LogP ]:
3.00

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.609

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36/37/39

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%