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UR-MB108

Names

[ CAS No. ]:
2412461-98-2

[ Name ]:
UR-MB108

Biological Activity

[Description]:

UR-MB108 (Compound 57) is a potent, selective ABCG2 (BCRP) inhibitor with an IC50 of 79 nM. UR-MB108 is stable in blood plasma[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Membrane Transporter/Ion Channel >> BCRP

[Target]

IC50: 79 nM (ABCG2 (BCRP))[1]


[References]

[1]. Frauke Antoni, et al. Tariquidar-related triazoles as potent, selective and stable inhibitors of ABCG2 (BCRP). Eur J Med Chem. 2020 Apr 1;191:112133.

Chemical & Physical Properties

[ Molecular Formula ]:
C40H38N6O4

[ Molecular Weight ]:
666.77

Related Compounds