RSV-IN-5

Names

[ CAS No. ]:
2415018-86-7

[ Name ]:
RSV-IN-5

Biological Activity

[Description]:

RSV-IN-5 (Compound 4) is a potent dual inhibitor of wild-type and mutant respiratory syncytial virus (RSV) fusion proteins. RSV-IN-5 exhibits potent anti-RSV activities against not only wild-type A2 F protein (EC50=2.0 nM), but also D486N-mutant F protein (EC50=8.1 nM)[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> RSV

[References]

[1]. Toru Yamaguchi-Sasaki, et al. Discovery of a potent dual inhibitor of wild-type and mutant respiratory syncytial virus fusion proteins through the modulation of atropisomer interconversion properties. Bioorg Med Chem. 2020 Dec 15;28(24):115818.

Chemical & Physical Properties

[ Molecular Formula ]:
C28H37N7O2

[ Molecular Weight ]:
503.64

Related Compounds