EGFR-IN-53

Names

[ CAS No. ]:
2418549-33-2

[ Name ]:
EGFR-IN-53

Biological Activity

[Description]:

EGFR-IN-53 (Compound 7) is a potent EGFR inhibitor with an IC50 of 8.264 µM. EGFR-IN-53 shows cytotoxic activity against cancer cell lines[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> JAK/STAT Signaling >> EGFR

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR

[Target]

EGFR:8.264 μM (IC50)

[References]

[1]. Abbas SY, et al. Synthesis and anticancer activity of thiourea derivatives bearing a benzodioxole moiety with EGFR inhibitory activity, apoptosis assay and molecular docking study. Eur J Med Chem. 2020 Jul 15;198:112363.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₁₃N₃O₂S

[ Molecular Weight ]:
287.34

Related Compounds