(±)-Taxifolin

Names

[ Name ]:
(±)-Taxifolin

[Synonym ]:
Dihydroquercetin
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)-
Distylin
(+)-Taxifolin
rac-taxifolin
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-, (2R-trans)-
5-18-05-00451
Taxifolin
rac-1'-acetoxydihydrochavicol acetate
rac-dihydrogalangal acetate
Taxifoliol
Dihydrogalangal acetate
(2R,3R)-2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydro-4H-chromen-4-one

Biological Activity

[Description]:

(±)-Taxifolin ((±)-Dihydroquercetin) is the racemate of Taxifolin. Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Autophagy >> Autophagy

Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase

[References]

[1]. Angelis A, et al. Bio-Guided Isolation of Methanol-Soluble Metabolites of Common Spruce (Picea abies) Bark by-Products and Investigation of Their Dermo-Cosmetic Properties. Molecules. 2016 Nov 21;21(11):1586.

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
687.6±55.0 °C at 760 mmHg

[ Melting Point ]:
239-240ºC

[ Molecular Formula ]:
C₁₅H₁₂O₇

[ Molecular Weight ]:
304.252

[ Flash Point ]:
264.2±25.0 °C

[ Exact Mass ]:
304.058289

[ PSA ]:
127.45000

[ LogP ]:
1.82

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.763

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xn,Xi

[ Risk Phrases ]:
22-36/37/38

[ Safety Phrases ]:
36-26

[ RTECS ]:
LK6920000

[ HS Code ]:
2942000000

Customs

[ HS Code ]: 2942000000