H-Phe(4-Br)-OH

Names

[ Name ]:
H-Phe(4-Br)-OH

[Synonym ]:
(S)-β-(p-Bromophenyl)alanine
H-PHE(4-BR)-OH
H-PHE(P-BR)-OH
para-bromo-L-phenylalanine
p-Bromo-L-phenylalanine
L-4-BROMOPHE
L-4-Bromo-phe-OH
H-P-BROMO-PHE-OH
4-Bromophenylalanine
p-Bromophenylalanine
L-4-Bromophenylalanine
(S)-4-Bromophenylalanine
4-Bromo-L-Phenylalanine
4-Bromo-L-Phe-OH
L-PHE(4-BR)
MFCD00063062
L-4-BR-PHE
Phenylalanine, 4-bromo-
L-p-Bromophenylalanine
(S)-2-Amino-3-(4-bromophenyl)propanoic acid
H-L-PHE(4-BR)-OH
(2S)-2-amino-3-(4-bromophenyl)propanoic acid
L-4-Bromo-Phenylalanine
L-4-BR-Phe-OH
(L)-(-)-4-bromophenylalanine

Biological Activity

[Description]:

(S)-2-Amino-3-(4-bromophenyl)propanoic acid is a phenylalanine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
368.4±32.0 °C at 760 mmHg

[ Melting Point ]:
265ºC (dec.)

[ Molecular Formula ]:
C₉H₁₀BrNO₂

[ Molecular Weight ]:
244.085

[ Flash Point ]:
176.6±25.1 °C

[ Exact Mass ]:
242.989487

[ PSA ]:
63.32000

[ LogP ]:
1.88

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.609

[ Storage condition ]:
Store at RT.

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic

[ Risk Phrases ]:
R25

[ Safety Phrases ]:
S45

[ RIDADR ]:
UN2811

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Efficient introduction of aryl bromide functionality into proteins in vivo.

FEBS Lett. 467(1) , 37-40, (2000)

Artificial proteins can be engineered to exhibit interesting solid state, liquid crystal or interfacial properties and may ultimately serve as important alternatives to conventional polymeric material...

Relaxing the substrate specificity of an aminoacyl-tRNA synthetase allows in vitro and in vivo synthesis of proteins containing unnatural amino acids.

FEBS Lett. 364(3) , 272-5, (1995)

It has previously been demonstrated that the unnatural amino acid p-Cl-phenylalanine can be attached to tRNA(Phe) by a modified phenylalanyl-tRNA synthetase with relaxed amino acid substrate specifici...

Neutron capture therapy for melanoma.

Basic Life Sci. 50 , 219-32, (1989)