(±)-1,2-Diolein

Names

[ Name ]:
(±)-1,2-Diolein

[Synonym ]:
1,2-Dioleoyl-DL-glycerol
rac-Glycerol 1,2-dioleate
1,2-Diolein
rac-1,2-Dioleoylglycerol
3-Hydroxypropane-1,2-diyl (9Z,9'Z)bis-octadec-9-enoate
GLYCEROL DIOLEATE
9-Octadecenoic acid, 1-(hydroxymethyl)-1,2-ethanediyl ester, (9Z,9'Z)-
3-hydroxy-1,2-propanediyl dioleate
1,2-Di(cis-9-octadecenoyl)-rac-glycerol
(±)-1,2-Dioleoylglycerol
DIOLEOYL-RAC-GLYCEROL
1,2-dioleoyl glycerol ester
[3-hydroxy-2-[(Z)-octadec-9-enoyl]oxypropyl] (Z)-octadec-9-enoate
cis-1,2-dioleoyl-rac-glycerol
UNII:ADK3G923Z3
1,2-Dioleoyl-rac-glycerol
(±)-1,2-Diolein
(9Z)-9-Octadecenoic acid
1,2-Dioleoylglycerol
3-Hydroxy-1,2-propanediyl (9Z,9'Z)bis(-9-octadecenoate)

Biological Activity

[Description]:

(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) is a PKC activator[1].

[Related Catalog]:

Signaling Pathways >> Epigenetics >> PKC

Research Areas >> Others

Signaling Pathways >> TGF-beta/Smad >> PKC

[In Vitro]

1,2-Diolein (50 μM; 5 min) increases Ca2+ influx significantly[1]. 1,2-Diolein (50 μM; 5 min) induces PKC activity of myoblasts cells[1]. Western Blot Analysis[1] Cell Line: myoblasts cells Concentration: 50 μM Incubation Time: 5 min Result: Induced PKC activity.

[References]

[1]. [1] Capiati DA, et al. Role of protein kinase C in 1,25(OH)(2)-vitamin D(3) modulation of intracellular calcium during development of skeletal muscle cells in culture. J Cell Biochem. 2000;77(2):200-212.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
670.8±35.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₉H₇₂O₅

[ Molecular Weight ]:
620.99

[ Flash Point ]:
186.3±19.4 °C

[ Exact Mass ]:
620.537964

[ PSA ]:
72.83000

[ LogP ]:
15.43

[ Vapour Pressure ]:
0.0±4.7 mmHg at 25°C

[ Index of Refraction ]:
1.477

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn: Harmful;F: Flammable;

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
36/37

[ RIDADR ]:
UN 1282 3

Precursor & DownStream

Precursor

DownStream

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