Pyren-1-ylmethanol
Names
[ CAS No. ]:
24463-15-8
[ Name ]:
Pyren-1-ylmethanol
[Synonym ]:
1-(Hydroxymethyl)pyrene
MFCD00029252
Pyrenemethanol
1-Pyrenylmethanol
1-PyreneMethanol
pyrenylmethan-1-ol
Chemical & Physical Properties
[ Density]:
1.321g/cm3
[ Boiling Point ]:
455.2ºC at 760mmHg
[ Melting Point ]:
123-126 °C(lit.)
[ Molecular Formula ]:
C17H12O
[ Molecular Weight ]:
232.27700
[ Flash Point ]:
207.5ºC
[ Exact Mass ]:
232.08900
[ PSA ]:
20.23000
[ LogP ]:
4.07630
[ Vapour Pressure ]:
4.46E-09mmHg at 25°C
[ Index of Refraction ]:
1.855
[ Storage condition ]:
2~8℃
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin .
[ Safety Phrases ]:
S26-S36/37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
UR2457242
[ HS Code ]:
2906299090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2906299090
[ Summary ]:
2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
Articles
Carcinogenesis 14(11) , 2267-70, (1993)
Rat liver cytosolic hydroxysteroid sulfotransferases form highly reactive sulfuric acid esters from some benzylic alcohols, such as 1-hydroxymethylpyrene. In this study we examined the expression of h...
Directing role of organic anion transporters in the excretion of mercapturic acids of alkylated polycyclic aromatic hydrocarbons.Drug Metab. Dispos. 35(10) , 1824-31, (2007)
Excretion of mercapturic acids of a xenobiotic is a good indicator for the formation of electrophilic intermediates. However, the route of excretion, urine or feces, is important for usage of a given ...
1-Sulfooxymethylpyrene is an electrophilic mutagen and ultimate carcinogen of 1-methyl- and 1-hydroxymethylpyrene.Biochem. Biophys. Res. Commun. 228(1) , 105-9, (1996)
1-Hydroxymethylpyrene and 1-sulfooxymethylpyrene were tested for complete carcinogenic activity by repeated s.c. injection in groups of 12 female Sprague-Dawley rats, respectively. A dose of 0.2 mumol...