Dapagliflozin impurity A

Names

[ Name ]:
Dapagliflozin impurity A

[Synonym ]:
(2S,3R,4R,5S,6R)-2-(4-chloro-3-((4-ethoxyphenyl)(hydroperoxy)methyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

Biological Activity

[Description]:

Dapagliflozin impurity A (Compound A) is a dapagliflozin peroxide, a genotoxic impurity, can cause damage to human genetic material at very low concentrations, leading to genetic mutations and possibly tumorigenesis[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Cao Jing, et al. Preparation of dapagliflozin peroxide. China, CN116410163 A. 2023-07-11.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₅ClO₈

[ Molecular Weight ]:
440.87

Dapagliflozin impurity A

Names

Biological Activity

Chemical & Physical Properties

Related Compounds