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Stellasterol

Names

[ CAS No. ]:
2465-11-4

[ Name ]:
Stellasterol

[Synonym ]:
5alpha-ergosta-7,22-dien-3beta-ol
Ergosta-7,22-dien-3-ol, (3β,5α,22E)-
(3β,5α,22E)-Ergosta-7,22-dien-3-ol
5α-Ergosta-7,22-dien-3β-ol
Stellasterol

Biological Activity

[Description]:

Stellasterol is a natural product. Stellasterol has high affinity towards Bcl-2 protein (Ki: 118.05 nM). Stellasterol is a weak α-glucosidase inhibitor[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Bcl-2 Family
Research Areas >> Others

[References]

[1]. Lau MF, et al. In vitro and in silico anticancer evaluation of a medicinal mushroom, Ganoderma neo-japonicum Imazeki, against human colonic carcinoma cells. Biotechnol Appl Biochem. 2021 Aug;68(4):902-917.  

[2]. Krisyanti Budipramana, et al. An Integrated In Silico and In Vitro Assays of Dipeptidyl Peptidase-4 and α-Glucosidase Inhibition by Stellasterol from Ganoderma austral. Sci. Pharm. 2019, 87(3). 21.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
487.5±44.0 °C at 760 mmHg

[ Melting Point ]:
149-150 °C

[ Molecular Formula ]:
C28H46O

[ Molecular Weight ]:
398.66

[ Flash Point ]:
213.0±20.7 °C

[ Exact Mass ]:
398.354858

[ PSA ]:
20.23000

[ LogP ]:
9.60

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.532

[ Storage condition ]:
2-8°C

Precursor & DownStream

Precursor

DownStream