neolitsine

Names

[ Name ]:
neolitsine

[Synonym ]:
5H-1,3-Benzodioxolo[6,5,4-de][1,3]benzodioxolo[5,6-g]quinoline, 6,7,7a,8-tetrahydro-7-methyl-, (7aS)-
(7aS)-7-Methyl-6,7,7a,8-tetrahydro-5H-bis[1,3]benzodioxolo[6,5,4-de:5',6'-g]quinoline
neolitsine

Biological Activity

[Description]:

Neolitsine ((+)-Neolitsine) is a vasodilator. Neolitsine can be isolated from the herb Cassytha filiformis. Neolitsine exhibits significant vasodilatory effects on precontracted rat aortic preparations with an IC50 of 0.29 μM[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[References]

[1]. Tsai TH, et al. Vasorelaxing alkaloids and flavonoids from Cassytha filiformis. J Nat Prod. 2008 Feb;71(2):289-91.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
485.1±34.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₉H₁₇NO₄

[ Molecular Weight ]:
323.34

[ Flash Point ]:
149.2±22.9 °C

[ Exact Mass ]:
323.115753

[ PSA ]:
40.16000

[ LogP ]:
4.11

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.671

Safety Information

[ Hazard Codes ]:
Xi