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AXC-715 trihydrochloride

Names

[ CAS No. ]:
2479276-17-8

[ Name ]:
AXC-715 trihydrochloride

Biological Activity

[Description]:

AXC-715 trihydrochloride is a TLR7/TLR8 dual agonist, extracted from patent WO2020168017 A1[1]. AXC-715 trihydrochloride, compound D from WO2020190734A1, can be used for synthesis of antibody-adjuvant immunoconjugates, comprising an antibody construct that binds programmed death-ligand 1 (PD-L1) linked to one or more adjuvants[2].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR)
Research Areas >> Inflammation/Immunology

[Target]

TLR7/TLR8[1]


[References]

[1]. Sung-Ju Moon, et al. Compositions containing, methods and uses of antibody-tlr agonist conjugates. Patent WO2020168017A1.

[2]. Shelley Erin ACKERMAN, et al. Immunoconjugates targeting pd-l1. Patent WO2020190734A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H28Cl3N5

[ Molecular Weight ]:
420.81

Related Compounds