COX-2-IN-19

Names

[ CAS No. ]:
2497530-12-6

[ Name ]:
COX-2-IN-19

Biological Activity

[Description]:

COX-2-IN-19 (Compound 24) is a potent COX-2 inhibitor with an IC50 of 1.76 μM. COX-2-IN-19 shows in vivo anti-inflammatory activity[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology
Signaling Pathways >> Immunology/Inflammation >> COX

[Target]

COX-2:1.76 μM (IC50)

COX-1:117.8 μM (IC50)


[References]

[1]. Munir A, et al. Synthesis, in-vitro, in-vivo anti-inflammatory activities and molecular docking studies of acyl and salicylic acid hydrazide derivatives. Bioorg Chem. 2020 Nov;104:104168.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H18N4O2S

[ Molecular Weight ]:
354.43

Related Compounds