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Acid-C3-SSPy

Names

[ CAS No. ]:
250266-79-6

[ Name ]:
Acid-C3-SSPy

[Synonym ]:
Butanoic acid, 4-(2-pyridinyldithio)-
4-(2-Pyridinyldisulfanyl)butanoic acid

Biological Activity

[Description]:

Acid-C3-SSPy is a cleavable DBA-DM4 linker used in the synthesis of DBA-DM4 (HY-128960), a drug-linker conjugate for ADC[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[References]

[1]. Samantha Congreve, et al. Antibody drug conjugates (ADC) Current status and mapping of ADC:s in clinical programs.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
411.6±41.0 °C at 760 mmHg

[ Molecular Formula ]:
C9H11NO2S2

[ Molecular Weight ]:
229.319

[ Flash Point ]:
202.7±27.6 °C

[ Exact Mass ]:
229.023117

[ LogP ]:
2.73

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.626

Related Compounds