Dynamin inhibitory peptide

Names

[ Name ]:
Dynamin inhibitory peptide

Biological Activity

[Description]:

Dynamin inhibitory peptide competitively blocks binding of dynamin to amphiphysin, thus preventing endocytosis. Dynamin inhibitory peptide blocks the dopamine D3 effect on GABAA receptors[1].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> Cytoskeleton >> Dynamin

[In Vitro]

Dynamin inhibitory peptide (50 μM) inhibits GABAAR endocytosis[1].

[References]

[1]. Guojun Chen, et al. Dopamine D3 receptors regulate GABAA receptor function through a phospho-dependent endocytosis mechanism in nucleus accumbens. J Neurosci. 2006 Mar 1;26(9):2513-21.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₇H₈₀N₁₈O₁₄

[ Molecular Weight ]:
1121.25000

[ Exact Mass ]:
1120.61000

[ PSA ]:
529.06000

[ Storage condition ]:
-20°C

Dynamin inhibitory peptide

Names

Biological Activity

Chemical & Physical Properties

Related Compounds