(S)-ATPO
Names
[ CAS No. ]:
252930-37-3
[ Name ]:
(S)-ATPO
[Synonym ]:
(S)-2-amino-3-[5-tertbutyl-3-(phosphono-methoxy)-4-isoxazolyl]propionic acid
HMS3260C06
ATPO
(R,S)-2-Amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid
Biological Activity
[Description]:
[Related Catalog]:
[In Vitro]
[References]
Chemical & Physical Properties
[ Boiling Point ]:
569.2±60.0 °C
[ Molecular Formula ]:
C11H19N2O7P
[ Molecular Weight ]:
322.25
[ Exact Mass ]:
322.09300
[ PSA ]:
165.92000
[ LogP ]:
1.14080
[ Storage condition ]:
2-8°C
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
Articles
J. Med. Chem. 39 , 1682-1691, (1996)
(RS)-2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA, 5) and the selective AMPA receptor antagonist (RS)-2-amino-3-[3-(carboxymethoxy)-5-methyl-4-isoxazolyl]propionic acid (AMOA, 7) ha...
Resolution, absolute stereochemistry, and enantiopharmacology of the GluR1-4 and GluR5 antagonist 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid.Chirality 11 , 752-9, (1999)
The phosphono amino acid, (RS)-2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl+ ++]propio nic acid (ATPO), is a structural hybrid between the NMDA antagonist (RS)-2-amino-7-phosphonoheptanoi...
Antagonist properties of a phosphono isoxazole amino acid at glutamate R1-4 (R,S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid receptor subtypes.Mol. Pharmacol. 53 , 590-6, (1998)
The activity of the (R, S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonist, (R,S) -2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl] propionic acid (ATPO)...