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AR-C102222

Names

[ CAS No. ]:
253771-21-0

[ Name ]:
AR-C102222

[Synonym ]:
2-Pyridinecarbonitrile, 5-[(4'-amino-5',8'-difluorospiro[piperidine-4,2'(1'H)-quinazolin]-1-yl)carbonyl]-, hydrochloride (1:1)
5-[(4'-Amino-5',8'-difluoro-1H,1'H-spiro[piperidine-4,2'-quinazolin]-1-yl)carbonyl]-2-pyridinecarbonitrile hydrochloride (1:1)

Biological Activity

[Description]:

AR-C102222 is a spirocyclic fluoropiperidine quinazoline selective iNOS inhibitor. AR-C102222 can be used for the research of neuropathic pain[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> NO Synthase
Research Areas >> Neurological Disease

[References]

[1]. Chris Walpole, et al. Diastereoselective synthesis of fluorinated piperidine quinazoline spirocycles as iNOS selective inhibitors. Tetrahedron Letters. Volume 53, Issue 24, 13 June 2012, Pages 2942-2947.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H17ClF2N6O

[ Molecular Weight ]:
418.828

[ Exact Mass ]:
418.112030

Related Compounds