N-ISOBUTYL-2,6,8-DECATRIENAMIDE

Names

[ Name ]:
N-ISOBUTYL-2,6,8-DECATRIENAMIDE

Biological Activity

[Description]:

Spilanthol is an orally active analgesic, neuroprotective, antioxidant, antimutagenic, anti-cancer, anti-inflammatory, antimicrobial and insecticidal compound.pilanthol can induce cAMP to inhibit negative regulation of urinary concentration mechanism. Spilanthol can be use as diuretic research[1][4][5].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Infection

Research Areas >> Others

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[Target]

Cyclic Adenosine monophosphate (cAMP)[5]

[References]

[1]. Alan F, et al. Spilanthol: occurrence, extraction, chemistry and biological activities. Elsevier. 2016:128-133

[2]. Déciga-Campos M, et al. Antinociceptive effect of Heliopsis longipes extract and affinin in mice. Planta Med. 2010 May;76(7):665-70.

[3]. Huang WC, et al. Spilanthol Inhibits COX-2 and ICAM-1 Expression via Suppression of NF-κB and MAPK Signaling in Interleukin-1β-Stimulated Human Lung Epithelial Cells. Inflammation. 2018 Oct;41(5):1934-1944.