(2-carbamoylphenoxy)acetic acid

Names

[ Name ]:
(2-carbamoylphenoxy)acetic acid

[Synonym ]:
2-Aminocarbonyl-phenoxyacetic acid
o-Carboxyamidophenoxyacetic acid
MFCD00025472
EINECS 246-940-7
ortho-carbamoylphenoxyacetic acid
(2-Carbamoylphenoxy)acetic Acid
2-Carbamoylphenoxyessigsaeure
2-Carbamoylphenoxyacetic acid
2-(Carboxymethoxy)benzamide
2-(2-Carbamoylphenoxy)acetic acid
Salicylamide O-acetic acid

Biological Activity

[Description]:

Salicylamide-O-acetic acid is a theophylline solubilizer[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Schulz HU, et al. Determination of the theophylline solubilizer salicylamide-O-acetic acid in serum and urine using high-performance liquid chromatography. J Pharm Biomed Anal. 1985;3(5):469-475.

Chemical & Physical Properties

[ Density]:
1.362g/cm3

[ Boiling Point ]:
419.1ºC at 760mmHg

[ Melting Point ]:
222°C

[ Molecular Formula ]:
C₉H₉NO₄

[ Molecular Weight ]:
195.17200

[ Flash Point ]:
207.3ºC

[ Exact Mass ]:
195.05300

[ PSA ]:
89.62000

[ LogP ]:
0.94920

[ Vapour Pressure ]:
8.94E-08mmHg at 25°C

[ Index of Refraction ]:
1.585

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AF7893000

CHEMICAL NAME :: Acetic acid, (o-carbamoylphenoxy)-

CAS REGISTRY NUMBER :: 25395-22-6

BEILSTEIN REFERENCE NO. :: 2109681

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C9-H9-N-O4

MOLECULAR WEIGHT :: 195.19

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BSIBAC Bolletino della Societe Italiana di Biologia Sperimentale. (Casa Editrice Idelson, Via A. de Gasperi, 55, 80133 Naples, Italy) V.2- 1927- Volume(issue)/page/year: 39,873,1963

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin .

[ Safety Phrases ]:
S26-S36/37/39

[ RTECS ]:
AF7893000

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%