Glyceryl monooleate

Names

[ Name ]:
Glyceryl monooleate

[Synonym ]:
Glyceryl cis-9-octadecenoate
9-Octadecenoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (9Z)-
Oleic monoglyceride
9-Octadecenoic acid (9Z)-, monoester with 1,2,3-propanetriol
1-monooleoyl-rac-glycerol
1-(cis-9-Octadecenoyl)-rac-glycerol
1-Monooleoylglycerol
rac-Glycerol 1-monooleate
Glycerin 1-monooleate
glycerol monooleate
rac 1-Oleoyl Glycerol
4,5-Dihydroxypentyl (7Z)-7-hexadecenoate
Glycerin monooleate
Oleic acid glycerol monoester
1,3-Dihydroxypropan-2-yl (9Z)-octadec-9-enoate
Glycerine monooleate
1-O-Oleyl-rac-glycerol
1-oleoyl glycerol
1-OLEOYLGLYCEROL
OLEOYL GLYCEROL
GLYCEROL OLEATE
9-Octadecenoic acid, 2,3-dihydroxypropyl ester, (9Z)-
1,3-Dihydroxy-2-propanyl (9Z)-9-octadecenoate
MFCD00042735
2,3-Dihydroxypropyl (9Z)-9-octadecenoate
2,3-Dihydroxypropyl oleate
GLYCEROL MONO-OLEATE
MONO OLEIN
Glycerine oleate
1-GLYCERYL OLEATE
Glycerol Alpha-Monooleate
GLYCERYL MONOOLEATE
2,3-Dihydroxypropyl (9Z)-octadec-9-enoate
a-Monoolein
DL-ALPHA-MONOOLEIN
Monoolein 9 C18:1
Danisco MO 90
GLYCEROL MONO OLEATE
Monoolein (VAN)
2-hydroxy-1-(hydroxymethyl)ethyl (9Z)-octadec-9-enoate
1-Oleoyl-rac-glycerol
2-Oleoylglycerol
Glyceryl Monooleate (VAN)
RAC.-1-OLEOYL-GLYCEROL BIOCHEMICA
(9Z)-9-Octadecenoic Acid 2,3-Dihydroxypropyl Ester
dl-α-Monoolein
Glycerol α-monooleate
UNII:D3AEF6S35P
α-Monoolein
rac-1-Monooleoylglycerol
7-Hexadecenoic acid, 4,5-dihydroxypentyl ester, (7Z)-
9-Octadecenoic acid (9Z)-, ester with 1,2,3-propanetriol
Monoolein
1-Mono(cis-9-octacenoyl)glycerol
EINECS 247-038-6
Aldo HMO

Biological Activity

[Description]:

Glycerol Monoleate is a nontoxic, biodegradable and biocompatible, lipophilic glycerol fatty acid ester. Glycerol monooleate has hemolytic properties. glycerol monooleate is used as an emulsifier and an absorption enhancer in combination with bile salts. Glycerol Monoleate can be used in drug delivery systems and siRNA delivery in Vitro[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Milak S, et al. Glycerol monooleate liquid crystalline phases used in drug delivery systems. Int J Pharm. 2015 Jan 30;478(2):569-87.

[2]. Zhen G, et al. Glycerol monooleate-based nanocarriers for siRNA delivery in vitro. Mol Pharm. 2012 Sep 4;9(9):2450-7.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
483.3±35.0 °C at 760 mmHg

[ Melting Point ]:
36 - 40ºC

[ Molecular Formula ]:
C₂₁H₄₀O₄

[ Molecular Weight ]:
356.540

[ Flash Point ]:
155.4±19.4 °C

[ Exact Mass ]:
356.292664

[ PSA ]:
66.76000

[ LogP ]:
6.71

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.479

[ Storage condition ]:
−20°C

[ Water Solubility ]:
chloroform: 50 mg/mL, clear, colorless

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RK1300000

CHEMICAL NAME :: Olein, mono-

CAS REGISTRY NUMBER :: 25496-72-4

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C21-H40-O4

MOLECULAR WEIGHT :: 356.61

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 5(5),391,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 5(5),391,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83110 No. of Facilities: 4016 (estimated) No. of Industries: 41 No. of Occupations: 51 No. of Employees: 74220 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83110 No. of Facilities: 9941 (estimated) No. of Industries: 81 No. of Occupations: 78 No. of Employees: 159120 (estimated) No. of Female Employees: 39063 (estimated)

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

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