HIV-1 inhibitor-23
Names
[ CAS No. ]:
2554622-28-3
[ Name ]:
HIV-1 inhibitor-23
Biological Activity
[Description]:
HIV-1 inhibitor-23 (compound 12a) is a highly potent HIV-1 non-nucleoside reverse transcriptase inhibitor, with EC50s of 24.9 nM and 10.4 nM for HIV-1 WT and HIV-1 K103N, respectively. HIV-1 inhibitor-23 has low cytotoxicity (CC50 > 221 μM) and a favorable in vitro microsomal stability[1].
[Related Catalog]:
[Target]
HIV-1 (WT):24.9 nM (EC50)
HIV-1 (K103N):10.4 nM (EC50)
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C30H26N6O4S
[ Molecular Weight ]:
566.63