Spermine Prodrug-1

Names

[ Name ]:
Spermine Prodrug-1

Biological Activity

[Description]:

Spermine Prodrug-1 (Compound 1) is a redox-sensitive spermine prodrug for the potential treatment of snyder robinson syndrome. Spermine Prodrug-1 inhibits wild-type (CMS-24949) and spermine synthase gene (SMS) mutant (CMS-26559, and CMS-6233) fibroblast cells with IC50s of 326.7, 198.5, and 244.1 μM, respectively[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Mukund P Tantak, et al. Development of a Redox-Sensitive Spermine Prodrug for the Potential Treatment of Snyder Robinson Syndrome. J Med Chem. 2021 Nov 11;64(21):15593-15607.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₄₅Cl₃N₄O₅

[ Molecular Weight ]:
576.00

Spermine Prodrug-1

Names

Biological Activity

Chemical & Physical Properties

Related Compounds