Pan-Trk-IN-2

Names

[ CAS No. ]:
2583778-77-0

[ Name ]:
Pan-Trk-IN-2

Biological Activity

[Description]:

Compound cpd-1 is a small molecule Trks inhibitor with good antitumor activity[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Trk Receptor

[References]

[1]. Pan S,et al. Structural Optimization and Structure-Activity Relationship Studies of 6,6-Dimethyl-4-(phenylamino)-6H-pyrimido[5,4-b][1,4]oxazin-7(8H)-one Derivatives as A New Class of Potent Inhibitors of Pan-Trk and Their Drug-Resistant Mutants. J Med Chem. 2022 Feb 10;65(3):2035-2058.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₁₈ClF₃N₆O₃

[ Molecular Weight ]:
506.86

Related Compounds