Lissamine rhodamine B

Names

[ Name ]:
Lissamine rhodamine B

[Synonym ]:
SulforhodaMine B 1GR
EINECS 220-025-2
4-[6-(Diethylamino)-3-(diethyliminio)-3H-xanthen-9-yl]-1,3-benzenedisulfonate
Ethanaminium, N-[6-(diethylamino)-9-(2,4-disulfophenyl)-3H-xanthen-3-ylidene]-N-ethyl-, inner salt, ion(1-)
Sulforhodamine B,laser grade
MFCD00067690
Sulforhodamine B
XYLENE RED B

Biological Activity

[Description]:

Lissamine rhodamine B is a red-fluorescent dye, it is a derivative of rhodamine. Lissamine rhodamine B can be used as a fluorescent probe to develop competitive aptamer fluorescence anisotropy/polarization (FA/FP) assays[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Lissamine rhodamine B (1 mg; 1 h; room temperature; dark) can be used to detect ochratoxin A (OTA) which is a common mycotoxin[1]. Lissamine rhodamine B have fluorescence properties, with the fluorescence detection conditions: excitation wavelength 555 nm, fluorescence emission spectrum detection 580 nm[1].

[In Vivo]

Lissamine rhodamine B can be used as an aradiotracer for imaging tumor mice by positron emission tomography (PET)[2].

[References]

[1]. Li Y, et al. Fluorescence Anisotropy-Based Signal-Off and Signal-On Aptamer Assays Using Lissamine Rhodamine B as a Label for Ochratoxin A. J Agric Food Chem. 2020 Apr 8;68(14):4277-4283.

[2]. Li X, et al. The Synthesis and Evaluations of the (6 8) Ga-Lissamine Rhodamine B (LRB) as a New Radiotracer for Imaging Tumors by Positron Emission Tomography. Biomed Res Int. 2016;2016:8549635.

Chemical & Physical Properties

[ Density]:
1.2175 (rough estimate)

[ Melting Point ]:
>300ºC(lit.)

[ Molecular Formula ]:
C₂₇H₃₀N₂O₇S₂

[ Molecular Weight ]:
557.659

[ Exact Mass ]:
557.142151

[ PSA ]:
147.72000

[ LogP ]:
6.17520

[ Index of Refraction ]:
1.6900 (estimate)

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
32041900

Articles

The dynamics of giant unilamellar vesicle oxidation probed by morphological transitions.

Biochim. Biophys. Acta 1838(10) , 2615-24, (2014)

We have studied the dynamics of Lissamine Rhodamine B dye sensitization-induced oxidation of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) giant unilamellar vesicles (GUVs), where the progression of...

Antiproliferative activity of flower hexane extract obtained from Mentha spicata associated with Mentha rotundifolia against the MCF7, KB, and NIH/3T3 cell lines.

J. Med. Food 15(11) , 955-8, (2012)

This study assessed the antiproliferative effect in vitro of the flower hexane extract obtained from Mentha spicata associated with Mentha rotundifolia against the human breast adenocarcinoma (MCF-7),...

Characterization of a genotoxic impact compound in Alternaria alternata infested rice as Altertoxin II.

Arch. Toxicol. 86(12) , 1911-25, (2012)

Toxicity-guided fractionation was used to identify DNA strand breaking impact compounds in extracts obtained from rice heavily infested with the Alternaria alternata strains DSM 62006 and DSM 62010. T...