Topilutamide
Names
[ CAS No. ]:
260980-89-0
[ Name ]:
Topilutamide
[Synonym ]:
UNII-A8EU2FXY13
2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-(2,2,2-trifluoroacetylamino)propanamide
Topilutamide
Biological Activity
[Description]:
Topilutamide is a topical nonsteroidal antiandrogen (NSAA).
[Related Catalog]:
[In Vivo]
Prostate cancer is the most common cancer and one of the leading causes of cancer deaths in men. One of the commonly used approaches to treat metastatic prostate cancer is via first-generation nonsteroidal anti-androgens (NSAAs), namely Flutamide, Nilutamide, Bicalutamide and Topilutamide[1].
[References]
[Related Small Molecules]
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GW4869
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GSK2795039
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AP 20187
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D-Luciferin
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Crotaline
Chemical & Physical Properties
[ Molecular Formula ]:
C13H11F6N3O5
[ Molecular Weight ]:
403.23400
[ Exact Mass ]:
403.06000
[ PSA ]:
131.23000
[ LogP ]:
3.99460
[ Storage condition ]:
2-8℃