5,6-diamino-3',6'-bis(diethylamino)spiro[2-benzofuran-3,9'-xanthene]-1-one

Names

[ Name ]:
5,6-diamino-3',6'-bis(diethylamino)spiro[2-benzofuran-3,9'-xanthene]-1-one

[Synonym ]:
5,6-Diamino-rhodamine B
5,6-Diamino-N,N,N',N'-tetraethyl-rhodamin
5,6-Diamino-N,N,N',N'-tetraethylrhodamine
DAR-2

Biological Activity

[Description]:

5,6-Diamino-N,N,N',N'-tetraethyl-rhodamin is a fluorescent indicator for NO[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Kojima H, et al. Fluorescent indicators for nitric oxide based on rhodamine chromophore. Tetrahedron Letters, 2000, 41(1): 69-72.

Chemical & Physical Properties

[ Density]:
1.31g/cm3

[ Boiling Point ]:
736.6ºC at 760 mmHg

[ Molecular Formula ]:
C₂₈H₃₂N₄O₃

[ Molecular Weight ]:
472.57900

[ Flash Point ]:
399.3ºC

[ Exact Mass ]:
472.24700

[ PSA ]:
94.05000

[ LogP ]:
6.27380

[ Vapour Pressure ]:
1.47E-21mmHg at 25°C

[ Index of Refraction ]:
1.684

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport

Articles

Bioimaging of nitric oxide with fluorescent indicators based on the rhodamine chromophore.

Anal. Chem. 73 , 1967, (2001)

Diaminofluoresceins are widely used for detection and imaging of nitric oxide (NO), but for biological applications, they have the disadvantages that the fluorescence of the fluorescein chromophore is...

H. Kojima et al.

Tetrahedron Lett. 41 , 69, (2000)