Phenylalanine,4-[bis(2-chloroethyl)amino]-N-formyl-

Names

[ Name ]:
Phenylalanine,4-[bis(2-chloroethyl)amino]-N-formyl-

[Synonym ]:
Formyl-L-valylglycin
N-formylsarcolysine
N-formyl-sarcolysin
N-[N-formyl-L-valyl=>glycine
FOR-PHENYLALANINE
N-FORMYL-L-PHENYLALNANINE
N-formylmelphalan
(+)-(S)-N-formylphenylalanine
N-formyl-3-phenyl-L-alanine
N-Formyl-L-valyl-glycin
N-formylphenylalanine
(S)-2-formylamino-3-phenylpropionic acid
4-[Bis-(2-chlor-aethyl)-amino]-N-formyl-phenylalanin
L-(HCO)-Val-Gly-OH
FOR-PHE-OH
FORMYL-L-PHENYLALANINE
4-[bis-(2-chloro-ethyl)-amino]-N-formyl-phenylalanine

Biological Activity

[Description]:

N-Formylsarcolysine has antitumor activity, and inhibits leukemia by increasing the Hb and erythrocyte levels and decreasing the number of leukocytes. N-Formylsarcolysine also involves in glioblastoma and other diseases research[1][2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Laukaitis V. Antitumorous activity and toxicity of amino acids and derivatives of peptides containing cytotoxine groups.(3. Diethylenimine phosphoric and thiophosphoric derivatives of aminophenyl and aminocyclohexyl alkaline acids and chlorethylamine derivatives of α amino acids)(Russian)[J]. Труды Академии наук Литовской ССР. Серия С: Биологические науки, 1975(2): 129-137.

[2]. ChenYY, et al. Quinoline derivative for treating glioblastoma: China, CN112294814[P]. 2021-02-02.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₁₈Cl₂N₂O₃

[ Molecular Weight ]:
333.21000

[ Exact Mass ]:
332.06900

[ PSA ]:
69.64000

[ LogP ]:
2.73910

Phenylalanine,4-[bis(2-chloroethyl)amino]-N-formyl-

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds