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Thalidomide-5,6-Cl

Names

[ CAS No. ]:
2648939-40-4

[ Name ]:
Thalidomide-5,6-Cl

Biological Activity

[Description]:

Thalidomide-5,6-Cl is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5,6-Cl can be connected to the ligand for protein by a linker to form PROTACs.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> Ligand for E3 Ligase

[In Vitro]

Thalidomide-5,6-Cl is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5,6-Cl can be connected to the ligand for protein by a linker to form PROTACs.

[References]

[1]. Zhang NN, et, al. A Thermostable mRNA Vaccine against COVID-19. Cell. 2020 Sep 3;182(5):1271-1283.e16.

Chemical & Physical Properties

[ Molecular Formula ]:
C13H8Cl2N2O4

[ Molecular Weight ]:
327.12

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds