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ITK/TRKA-IN-1

Names

[ CAS No. ]:
2655557-54-1

[ Name ]:
ITK/TRKA-IN-1

Biological Activity

[Description]:

ITK/TRKA-IN-1 is a dual inhibitor of IL-2-inducible T-cell kinase (ITK) and tropomyosin receptor kinase A (TRKA) with an IC50 value of 1.0 nM and 96 % inhibition, respectively.

[Related Catalog]:

Research Areas >> Inflammation/Immunology
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Itk

[References]

[1]. Bagley SW, et al. Benzimidazole Derivatives. WO2021124155A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H30F2N6O2

[ Molecular Weight ]:
484.54


Related Compounds