TMDJ-035

Names

[ Name ]:
TMDJ-035

Biological Activity

[Description]:

TMDJ-035 is a selective RyR2 inhibitor. TMDJ-035 suppresses abnormal Ca2+ waves and transients in isolated cardiomyocytes from RyR2-mutated mice. TMDJ-035is a tool for studying the mechanism and dynamics of RyR2 channel gating[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel

Research Areas >> Inflammation/Immunology

[References]

[1]. Ryosuke Ishida, et al. A potent and selective cis-amide inhibitor of ryanodine receptor 2 as a candidate for cardiac arrhythmia treatment. European Journal of Medicinal Chemistry

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₂F₃N₅O

[ Molecular Weight ]:
347.29

TMDJ-035

Names

Biological Activity

Chemical & Physical Properties

Related Compounds