PRMT5-IN-25

Names

[ CAS No. ]:
2691869-82-4

[ Name ]:
PRMT5-IN-25

Biological Activity

[Description]:

PRMT5-IN-25 (compound 503) is a potent PRMT5 inhibitor with an Ki value of 0.06 nM. PRMT5-IN-25 shows antiproliferative[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Epigenetics >> Histone Methyltransferase

[Target]

PRMT5:0.06 nM (Ki)


[References]

[1]. Jennifer Rebecca Allen, et al. Novel prmt5 inhibitors. WO2021163344A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H21F3N6O

[ Molecular Weight ]:
466.46

Related Compounds