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EPZ-719

Names

[ CAS No. ]:
2697176-16-0

[ Name ]:
EPZ-719

Biological Activity

[Description]:

EPZ-719 is a novel and potent SETD2 inhibitor ( IC50 = 0.005 μM) with a high selectivity over other histone methyltransferases.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Epigenetics >> Histone Methyltransferase

[References]

[1]. Lampe JW, et al. Discovery of a First-in-Class Inhibitor of the Histone Methyltransferase SETD2 Suitable for Preclinical Studies. ACS Med Chem Lett. 2021 Aug 24;12(10):1539-1545.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H31FN4O3S

[ Molecular Weight ]:
450.57

Related Compounds