Antimalarial agent 8

Names

[ Name ]:
Antimalarial agent 8

Biological Activity

[Description]:

Antimalarial agent 8 (Compound 7e) is a novel orally active class of antimalarials. Antimalarial agent 8 is potent in vitro against P. falciparum and is orally efficacious (40 mg/kg) in an in vivo mouse model of malaria[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. Mathew J, et al. Malaria Box-Inspired Discovery of N-Aminoalkyl-β-carboline-3-carboxamides, a Novel Orally Active Class of Antimalarials. ACS Med Chem Lett. 2022;13(3):365-370.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₁Cl₃N₄O

[ Molecular Weight ]:
463.79

Antimalarial agent 8

Names

Biological Activity

Chemical & Physical Properties

Related Compounds